Silicosis

Back to Library

Silicosis is caused by inhalation of quartz-containing dust.
Silicosis is caused by inhalation of silicon dioxide (quartz).
Short heavy doses produce acute silicosis with pulmonary oedema and alveolar exudation.
Prolonged exposure leads to formation of multiple fibrous nodules composed of collagen in the lungs.
These expand and cause extensive destruction of lung tissue.
PMF may also develop. Histologically, silica particles can be seen in nodules, using polarized light .
The pathogenesis of silicosis is thought to be a toxic effect on macrophages, which stimulates cytokine generation, precipitating fibrogenesis.
In silicosis, nodules of collagen contain silica particles. In this case, as is common when coal-mining exposure has occurred, there is additional carbon pigmentation, resulting in black peripheral staining.
Interested in translating health topics to somali language!

We give here simplified and accurate information about the disease Info@somalidoc.com


DISCLAIMER: This website is provided for general information and it's run by medical students for medical students only and is not a substitute for professional medical advice. We are not responsible or liable for any diagnosis or action made by a user based on the content of this website. We are not liable for the contents of any external websites listed, nor do we endorse any commercial product or service mentioned or advised on any of the sites. Always consult your own doctor if you are in any way concerned about your health

Advertising | Conditions of use | Privacy policy | Webmaster
Copyright 2007 [
www.somalidoc.com]. All rights reserved.
Revised: 02-11-2014.