Somali Medical Forums

Allied Health Professions => Pre-Pharmacy and Pharmacy => Topic started by: Pharmacist on November 04, 2007, 07:48:33 AM

Title: Teratogenic Drugs?!
Post by: Pharmacist on November 04, 2007, 07:48:33 AM
Does anyone have list of harmful drugs during pregnancy?
Please post it here or give me a link?
Thanks in advance

Real Pharmacist
Title: Re: Teratogenic Drugs?!
Post by: Admin on November 04, 2007, 08:47:21 PM
I will try to get the list for you, but you know new drugs are not allowed to be tested on pregnant ladies, so the effects of a lot of drugs are not known, so it's better to ask in this way: Does anyone know a list of safe drugs during pregnancy?

But there are notorious drugs with harmful side effects in pregnant ladies and these are some samples:

Thalidomide----amelia, or micromelia (absence os limbs or very short limbs)
Phenytoin----fetal hydantoin syndrome
Chloramphenicol----grey baby syndrome
Tetracyclines-----teeth malformation and discoloration
Aspirin----early closure of ductus arteriosus
Carbamazepine-----cleft lip and palate
Warfarin----Recommended use only during the 13th to 36th week of pregnancy because of fetal abnormalities associated with it's use during the first trimester - chondrodysplasia punctata - and after the 36th week - fetal intracerebral bleeding.
Lithium----Increases the incidence of Ebstein's anomaly, increased associated miscarriage risk with lithium treatment during pregnancy.
Sodium valproate----Increased risk (x20) of infant with spina bifida.
ACE inhibitors---Renal damage
Cocaine----Abnormal fetal dev. & addiction.
DES---Vaginal clear cell adenocarcinoma.
Iodide---Cong. goiter or hypothyroidism.
Isotretinoin---Ear,Brain & Heart malformation.

That's for now, the list will follow
Dr.Mahdi



Title: Re: Teratogenic Drugs?!
Post by: Pharmacist on November 06, 2007, 03:08:36 PM
Thanks dr.mahdi,
It was really informative, and I am waiting the list

Real Pharmacist
Title: Re: Teratogenic Drugs?!
Post by: Admin on November 11, 2007, 02:00:30 AM
Withdrawn Drugs From Market (http://en.wikipedia.org/wiki/List_of_withdrawn_drugs)
Conditions commonly encountered in the pregnant woman that may require medications & the safe choices. (http://www.theberries.ns.ca/ARchives/drugs_pregnancy.html)
Check the risk of your drugs on the fetus (http://www.safefetus.com/)
Medications and drug use during pregnancy (http://health.yahoo.com/pregnancy-resources/medications-and-drug-use-during-pregnancy/healthwise--tn7382.html)

Dr.Mahdi
Title: Re: Teratogenic Drugs?!
Post by: Somstudent on February 25, 2013, 05:48:38 PM
Vitamin A is also Teratogenic, its not a drug but its a supplement that cause major damage to the unborn infant.