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Shock is a clinical state associated with generalized failure of tissue perfusion.
In contrast to local failure of vascular flow, a systemic reduction in tissue blood flow, manifest by profound low blood pressure (hypotension), is clinically termed shock.
Among the many causes of shock are:
severe failure of the pumping mechanism of the heart (cardiogenic shock)
blockage of major arteries (obstructive shock)
lack of blood to pump (hypovolaemic shock) due to
haemorrhage or severe fluid loss.
Abnormal dilatation of peripheral vessels causing lack of venous return of blood may also be responsible, arising in cases of septicaemic shock/endotoxic shock, anaphylactic shock and neurogenic shock.
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Revised: 02-11-2014.