Author Topic: Case (24)  (Read 4077 times)

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Offline Muna1

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Case (24)
« on: December 25, 2007, 08:12:52 PM »
A 64-year-old female is brought to the Emergency Department by her family, who are concerned about her increasing confusion over the past 2 days. On examination she is found to be pyrexial at 38؛C. Blood tests reveal:
      Hb 9.6 g/dl
      Platelet s65 * 109/l
      WCC 11.1 * 109/l
      Urea 23.1 mmol/l
      Creatinine 366 ┬Ámol/l

What is the most likely diagnosis?




Offline Kassim

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Re: Case (24)
« Reply #1 on: December 25, 2007, 10:24:00 PM »
It  looks like, Thrombotic thrombocytopenic purpura (TTP)
Classically, the following five symptoms are indicative of this elusive disease: Fluctuating neurological symptoms, such as bizarre behavior, altered mental status, (confusion over the past 2 days)
Stroke or headaches (65%)
Kidney failure (46%); Urea 23.1 mmol/l, Creatinine 366 ┬Ámol/l
Fever (33%); pyrexial at 38؛C
Thrombocytopenia, Platelet s65 * 109/l
Microangiopathic hemolytic anaemia, Hb 9.6 g/dl
Treatment
Intravenous (IV) plasma exchange, also called plasmapheresis, is the present standard of treatment for TTP. During the plasma exchange, the inhibitory antibodies are removed and the plasma is replenished with the deficient protease.
hope this is the correct unswer
Kassim
    
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Offline Muna1

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Re: Case (24)
« Reply #2 on: December 26, 2007, 10:07:27 PM »
well done kasem.it is correct

Offline Admin

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Re: Case (24)
« Reply #3 on: December 27, 2007, 12:29:39 AM »
Congrats, 15 points of this case goes to Kassim
"you never cure a patient, you treat pain often but you always comfort the patient."
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